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  Some Known Incorrect Statements About Can You Get High From Too Much Cbd? - Merry Jane It likewise binds to cannabinoid 2 (CB2) receptors situated in the brainstem and hippocampus, which has links to memory and feelings. Immune cells, bone cells, and spleen and liver cells likewise include CB2 receptors. This widespread circulation of cannabinoid receptors is the factor why THC produces such powerful physical and mental results. CBD does not bind to either CB1 or CB2 receptors. According to a 2018 evaluation post, CBD might  medicinal hemp oil for sale reduce the capability of THC and other cannabinoids to bind to the CB1 receptor's. This might reduce the psychedelic effects of THC and might increase the variety of flowing cannabinoids. A 2018 evaluation in Surgical Neurology International suggests that CBD might lower inflammation in the brain by indirectly interacting with CB2 receptors. Anecdotal proof and initial research study recommend that CBD may help deal with a ran